Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15845985 | 0.86 | NPC1 (0.40) | NPC1HTTRAB9AKDM4EALOX12 | |
| SCHEMBL29133119 | 0.77 | HTR2A (0.40) | TRIM24TRIM33ALDH1A1HTR2AHTR2C | |
| SCHEMBL28102228 | 0.74 | TRIM24 (0.39) | TRIM24TRIM33NPC1HTTRAB9A | |
| SCHEMBL27987069 | 0.71 | TRIM24 (0.47) | TRIM24TRIM33NPC1HTTRAB9A | |
| SCHEMBL29132983 | 0.71 | TRIM24 (0.43) | TRIM24TRIM33NPC1HTTRAB9A | |
| SCHEMBL657873 | 0.71 | ADH1B (0.41) | TRIM24TRIM33NPC1RAB9AKDM4E | |
| SCHEMBL4106646 | 0.70 | TRIM24 (0.44) | TRIM24TRIM33NPC1HTTRAB9A | |
| SCHEMBL24107663 | 0.69 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2ALDH1A1SYKL3MBTL1 | |
| SCHEMBL29587068 | 0.69 | AKT1 (0.34) | NPC1RAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL398730 | 0.69 | AKT1 (0.34) | NPC1RAB9ASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |