Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622169 | 1.00 | MAPT (0.39) | MAPTKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27736352 | 0.85 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL38660064 | 0.81 | GAA (0.51) | MAPTKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29141516 | 0.79 | ERN1 (0.51) | MAPTKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27982666 | 0.78 | KMO (0.49) | GRM4MEN1KMT2AL3MBTL1 | |
| SCHEMBL29133015 | 0.76 | MAOB (0.37) | MAPTKDM4EALDH1A1HPGDABCB1 | |
| SCHEMBL30622206 | 0.76 | MAOB (0.37) | MAPTKDM4EALDH1A1HPGDABCB1 | |
| SCHEMBL30622160 | 0.76 | HDAC4 (0.42) | KDM4EALDH1A1RAB9AMAPK1PRMT5 | |
| SCHEMBL28878342 | 0.76 | HDAC4 (0.42) | KDM4EALDH1A1RAB9AMAPK1PRMT5 | |
| SCHEMBL4312617 | 0.75 | ALDH1A1 (0.54) | MAPTALDH1A1HPGDABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |