Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622160 | 1.00 | HDAC4 (0.42) | HDAC4PRMT5WDR77IDO1DHODH | |
| SCHEMBL16780503 | 0.84 | GABRG2 (0.46) | HDAC4PRMT5WDR77DHODHGABRG2 | |
| SCHEMBL28148553 | 0.79 | PRMT5 (0.41) | HDAC4PRMT5WDR77DHODHSLC6A2 | |
| SCHEMBL28244882 | 0.78 | GRIN1 (0.41) | HDAC4PRMT5WDR77DHODHGABRG2 | |
| SCHEMBL16780594 | 0.77 | HDAC4 (0.46) | HDAC4PRMT5WDR77DHODHGABRG2 | |
| SCHEMBL30719418 | 0.77 | HDAC4 (0.46) | HDAC4PRMT5WDR77DHODHGABRG2 | |
| SCHEMBL16787399 | 0.76 | GRIN2B (0.45) | HDAC4PRMT5WDR77DHODHSLC6A2 | |
| SCHEMBL29091546 | 0.76 | KMO (0.46) | HDAC4PRMT5WDR77DHODHSLC6A2 | |
| SCHEMBL28104975 | 0.76 | ALDH1A1 (0.42) | HDAC4PRMT5WDR77DHODHSLC6A2 | |
| SCHEMBL30622169 | 0.76 | MAPT (0.39) | PRMT5WDR77KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-115304592-A | Diazosulfide heat shock delayed fluorescent material and preparation method thereof | 兰州大学 | 2022-11-08 | — | — | CN | disclosed |