SCHEMBL29686385

SCHEMBL29686385

CS(=O)(=O)c1ccc(Nc2ncccc2C(N)=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.71
SMN1; SMN2 Q16637 6/20 0.71
NPC1 O15118 5/20 0.71
MAPT P10636 5/20 0.71
AHR P35869 1/20 0.71
ALDH1A1 P00352 5/20 0.57
LMNA P02545 1/20 0.55
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
KCNH2 Q12809 1/20 0.54
DHODH Q02127 4/20 0.51
HTT P42858 2/20 0.51
SYK P43405 3/20 0.51
HPGD P15428 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29898269 0.83 RAB9A (1.00) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL28824955 0.83 RAB9A (1.00) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL479805 0.81 DHODH (0.76) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL29133468 0.81 RAB9A (0.74) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL28824933 0.80 RAB9A (0.76) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL29898323 0.80 RAB9A (0.76) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL29421217 0.80 RAB9A (0.73) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL29898256 0.80 RAB9A (0.78) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL28949513 0.80 RAB9A (0.78) RAB9ASMN1; SMN2NPC1MAPTAHR
SCHEMBL10169304 0.78 SYK (0.52) RAB9ASMN1; SMN2NPC1MAPTAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022117016-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳微芯生物科技股份有限公司 2022-06-09 WO disclosed