Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MLYCD | O95822 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308968 | 0.84 | GRM5 (0.40) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL5429605 | 0.82 | GRM5 (0.54) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL5420477 | 0.81 | HPGD (0.53) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL5312194 | 0.81 | SMN1; SMN2 (0.55) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL991484 | 0.81 | GRM5 (0.59) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL12844304 | 0.81 | GRM5 (0.52) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL3612518 | 0.79 | KMT2A (0.50) | HSP90AA1HPGDALDH1A1LMNACYP1A2 | |
| SCHEMBL5430899 | 0.79 | HCAR3 (0.54) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL29133579 | 0.79 | GRM5 (0.51) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL12776433 | 0.78 | MLYCD (0.53) | GRM5HSP90AA1HSP90AB1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046724-A1 | Expansible Biocompatible Coats Comprising a Biologically Active Substance | AVIDAL VASCULAR GMBH (DE) | 2011-02-24 | — | — | US | claimed |
| EP-2271396-A2 | EXPANSIBLE BIOCOMPATIBLE COATS COMPRISING A BIOLOGICALLY ACTIVE SUBSTANCE | Avidal Vascular Gmbh (DE) | 2011-01-12 | — | — | EP | claimed |
| WO-2009121565-A2 | EXPANSIBLE BIOCOMPATIBLE COATS COMPRISING A BIOLOGICALLY ACTIVE SUBSTANCE | AVIDAL VASCULAR GMBH (DE) | 2009-10-08 | — | — | WO | claimed |
| US-20110046724-A1 | Expansible Biocompatible Coats Comprising a Biologically Active Substance | AVIDAL VASCULAR GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2271396-A2 | EXPANSIBLE BIOCOMPATIBLE COATS COMPRISING A BIOLOGICALLY ACTIVE SUBSTANCE | Avidal Vascular Gmbh (DE) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009121565-A2 | EXPANSIBLE BIOCOMPATIBLE COATS COMPRISING A BIOLOGICALLY ACTIVE SUBSTANCE | AVIDAL VASCULAR GMBH (DE) | 2009-10-08 | — | — | WO | disclosed |
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | PURDUE RESEARCH FOUNDATION | 2003-02-13 | — | — | US | disclosed |
| WO-2002030466-A2 | PHARMACEUTICAL APPLICATIONS OF HYDROTROPIC AGENTS, POLYMERS THEREOF, AND HYDROGELS THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | HMGB2, HTT, ABCG2 | GRM5 4501/4885HSP90AA1 23/4885HSP90AB1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.