Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4651041 | 0.69 | MEN1 (0.46) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25611303 | 0.69 | POLB (0.42) | POLBCYP1A2MEN1KMT2AGABRP | |
| SCHEMBL30761561 | 0.69 | GABRP (0.40) | MEN1KMT2APARP1GABRPGABRD | |
| SCHEMBL440739 | 0.68 | PDE3B (0.37) | POLBCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL8492592 | 0.68 | POLB (0.37) | POLBCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL580070 | 0.67 | POLB (0.39) | POLBCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL2850885 | 0.67 | MEN1 (0.47) | POLBMEN1KMT2APARP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4651135 | 0.67 | PDE3B (0.36) | POLBCYP1A2MEN1KMT2APARP1 | |
| SCHEMBL9704535 | 0.67 | POLB (0.51) | POLBCYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL3715656 | 0.66 | PARP1 (0.41) | POLBCYP1A2MEN1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337289-A | Tetracyclic compounds for the treatment of brain disorders | 加利福尼亚大学董事会 | 2024-01-02 | — | — | CN | disclosed |