SCHEMBL29133683

SCHEMBL29133683

C=C(C)c1ccccc1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
CYP2D6 P10635 3/20 0.47
CYP2C19 P33261 3/20 0.47
CYP3A4 P08684 2/20 0.47
PTPN1 P18031 1/20 0.45
BCL2 P10415 1/20 0.45
BCL2L1 Q07817 1/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
HTR2A P28223 1/20 0.42
CALM1 P0DP23 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
NFKB1 P19838 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
HIF1A Q16665 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SCN1A P35498 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21556877 0.85 TSHR (0.44) TSHRCYP2D6CYP2C19CYP3A4CYP1A2
SCHEMBL27540021 0.83 TSHR (0.52) TSHRCYP2D6CYP2C19CYP3A4PTPN1
SCHEMBL9126315 0.83 TSHR (0.52) TSHRCYP2D6CYP2C19CYP3A4PTPN1
SCHEMBL9806336 0.82 LMNA (0.53) TSHRALDH1A1MAPTSCN1ASCN2A
SCHEMBL21556951 0.81 TSHR (0.41) TSHRCYP2D6CYP2C19CYP3A4PTPN1
SCHEMBL9806292 0.81 TSHR (0.56) TSHRCYP2D6CYP2C19CYP3A4BCL2
SCHEMBL9806310 0.80 TSHR (0.53) TSHRCYP2D6CYP2C19CYP3A4PTPN1
SCHEMBL1044513 0.80 TSHR (0.58) TSHRCYP2D6CYP2C19CYP3A4PTPN1
SCHEMBL3284499 0.79 ALDH1A1 (0.43) TSHRCYP2D6CYP2C19CYP3A4ALDH1A1
Acetic Acid SCHEMBL28245857 0.78 TSHR (0.71) TSHRCYP2D6CYP2C19CYP3A4PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117321092-A Methacrylic copolymer, methacrylic resin composition, method for producing same, and molded article 株式会社可乐丽 2023-12-29 CN disclosed