SCHEMBL3284499

SCHEMBL3284499

C=C(C)c1ccccc1CCc1ccccc1C(=C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
LMNA P02545 2/20 0.43
FOLH1 Q04609 1/20 0.41
KDM4E B2RXH2 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ADRB2 P07550 1/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 3/20 0.36
SCN1A P35498 1/20 0.34
SCN2A Q99250 1/20 0.34
SCN3A Q9NY46 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
MEN1 O00255 2/20 0.33
TSHR P16473 2/20 0.33
ATM Q13315 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9806336 0.90 LMNA (0.53) ALDH1A1LMNAKDM4ESMN1; SMN2ADRB2
SCHEMBL29590143 0.89 ALDH1A1 (0.40) ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2
SCHEMBL712790 0.89 ALDH1A1 (0.40) ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2
SCHEMBL2557195 0.87 TAAR1 (0.50) ALDH1A1LMNAFOLH1SMN1; SMN2CYP3A4
SCHEMBL9614146 0.86 LMNA (0.38) ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2
SCHEMBL721716 0.86 LIPG (0.46) ALDH1A1LMNAHTTCYP3A4CYP2D6
SCHEMBL31093056 0.86 LIPG (0.46) ALDH1A1LMNAHTTCYP3A4CYP2D6
SCHEMBL20922988 0.84 TAAR1 (0.52) ALDH1A1LMNAFOLH1SMN1; SMN2
SCHEMBL721901 0.84 LIPG (0.53) HTTMAPTKMT2ACYP3A4MEN1
SCHEMBL31115693 0.84 LIPG (0.53) HTTMAPTKMT2ACYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678526-B1 Ethylene polymers having both ends modified and processes for the production thereof TONEN CORP (JP) 1998-04-01 EP claimed
EP-0678526-A2 Ethylene polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1995-10-25 EP claimed
EP-0530408-A1 Olefin polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1993-03-10 EP claimed
US-7709687-B2 Dicarbanionic initiator, a process for the preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-05-04 US disclosed
US-20070197723-A1 NOVEL DICARBANIONIC INITIATOR, A PROCESS FOR THE PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2007-08-23 US disclosed
US-20040253442-A1 Method of forming a nanoporous film and compositions useful in such methods MUBAREKYAN ERVIN (US) 2004-12-16 US disclosed
EP-0678526-B1 Ethylene polymers having both ends modified and processes for the production thereof TONEN CORP (JP) 1998-04-01 EP disclosed
EP-0678526-A2 Ethylene polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1995-10-25 EP disclosed
EP-0532804-B1 An ethylene polymer and a process for its production TONEN CORP (JP) 1995-06-28 EP disclosed
US-5367033-A Hydroxy or carboxy endcapped polyethylene reacted with diol or diacid TONEN CORPORATION (JP) 1994-11-22 US disclosed
US-5334678-A Using a coordination catalyst containing a vanadium chelate compound and a dialkylaluminum halide TONEN CORPORATION (JP) 1994-08-02 US disclosed
EP-0532804-A1 An ethylene polymer and a process for its production Tonen Corporation (JP) 1993-03-24 EP disclosed
EP-0530408-A1 Olefin polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1993-03-10 EP disclosed