SCHEMBL29133889

SCHEMBL29133889

COc1cc(C=NCCS(=O)(=O)O)cc(OC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.47
PTGS2 P35354 3/20 0.47
CYP1B1 Q16678 5/20 0.44
CYP1A1 P04798 4/20 0.44
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
ABL1 P00519 4/20 0.39
BCR P11274 4/20 0.39
ALOX5 P09917 3/20 0.39
TTR P02766 2/20 0.39
ABCB1 P08183 2/20 0.39
NQO2 P16083 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
PTGS1 P23219 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29133885 1.00 CA2 (0.47) CA2PTGS2CYP1B1CYP1A1CA12
SCHEMBL29133831 0.84 CA2 (0.56) CA2PTGS2CA12CA1CA9
SCHEMBL29133834 0.84 CA2 (0.56) CA2PTGS2CA12CA1CA9
SCHEMBL29133830 0.82 PTGS2 (0.49) PTGS2CYP1B1CYP1A1KDM4EMEN1
SCHEMBL29133828 0.82 PTGS2 (0.49) PTGS2CYP1B1CYP1A1KDM4EMEN1
SCHEMBL5383595 0.78 CYP1B1 (0.47) PTGS2CYP1B1CYP1A1ABL1BCR
SCHEMBL5383597 0.78 CYP1B1 (0.47) PTGS2CYP1B1CYP1A1ABL1BCR
SCHEMBL29133865 0.78 PTGS2 (0.51) CA2PTGS2CYP1A1CA12CA9
SCHEMBL29133869 0.78 PTGS2 (0.51) CA2PTGS2CYP1A1CA12CA9
SCHEMBL29133838 0.76 SHBG (0.61) CA2PTGS2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116982622-A Taurine derivative plant growth regulator and application thereof 河南沐天农业科技有限公司 2023-11-03 CN claimed