Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3744533 | 0.84 | MAPK1 (0.48) | CTSLTYMSTHRBTHRAALDH1A1 | |
| SCHEMBL18459324 | 0.84 | TYMS (0.40) | CTSLTYMSTHRBTHRAALDH5A1 | |
| SCHEMBL27624619 | 0.82 | SERPINE1 (0.41) | TYMSTHRBTHRAALDH5A1ABAT | |
| SCHEMBL39880 | 0.81 | ABL1 (0.49) | THRBTHRAALDH1A1MEN1KMT2A | |
| SCHEMBL10766945 | 0.79 | MAOB (0.47) | TYMSTHRBTHRAALDH5A1ABAT | |
| Acetic Acid SCHEMBL28463886 | 0.78 | ABL1 (0.46) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL9282538 | 0.77 | CFD (0.49) | CTSLALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1215245 | 0.77 | THRB (0.49) | TYMSTHRBTHRAALDH1A1MEN1 | |
| SCHEMBL30596851 | 0.77 | THRB (0.49) | TYMSTHRBTHRAALDH1A1MEN1 | |
| SCHEMBL27557556 | 0.76 | THRB (0.36) | CTSLTYMSTHRBTHRAALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112004816-B | PRC2 inhibitors | 米拉蒂医疗股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-114269748-A | Imidazo [1,2-c ] pyrimidine derivatives as PRC2 inhibitors for the treatment of cancer | 米拉蒂医疗股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-112004816-A | PRC2 inhibitors | 米拉蒂医疗股份有限公司 | 2020-11-27 | — | — | CN | disclosed |