SCHEMBL3744533

SCHEMBL3744533

C=CC(=O)Oc1ccc(Br)cc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SMN1; SMN2 Q16637 5/20 0.43
HPGD P15428 3/20 0.43
LMNA P02545 3/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
TSHR P16473 1/20 0.43
ALOX15 P16050 5/20 0.41
ALOX12 P18054 2/20 0.40
TYMS P04818 1/20 0.38
NCEH1 Q6PIU2 1/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29134091 0.84 CTSL (0.38) MAPK1ALDH1A1HPGDLMNAMEN1
SCHEMBL39880 0.83 ABL1 (0.49) ALDH1A1TDP1L3MBTL1SMN1; SMN2HPGD
SCHEMBL27850463 0.83 DGAT1 (0.42) MAPK1ALDH1A1L3MBTL1SMN1; SMN2HPGD
SCHEMBL28464660 0.81 PTGDR2 (0.55) ALDH1A1TDP1L3MBTL1SMN1; SMN2HPGD
SCHEMBL28673341 0.81 ALOX15 (0.43) SMN1; SMN2HPGDLMNAMAPTKMT2A
SCHEMBL28971707 0.79 KDM4E (0.43) MAPK1L3MBTL1SMN1; SMN2HPGDLMNA
Acetic Acid SCHEMBL28463886 0.79 ABL1 (0.46) ALDH1A1TDP1L3MBTL1SMN1; SMN2HPGD
SCHEMBL21753722 0.79 ALDH1A1 (0.58) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL10959094 0.79 MAPK1 (0.58) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL1215245 0.78 THRB (0.49) ALDH1A1HPGDMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9591848-B2 Biofilm resistant polymer materials Abilene Christian Univ. (US) 2017-03-14 US claimed
US-20120208916-A1 Biofilm Resistant Polymer Materials CAVITT T BRIAN (US) 2012-08-16 US claimed
US-20090304621-A1 Biofilm Resistant Polymer Materials ABILENE CHRISTIAN UNIVERSITY 2009-12-10 US claimed
US-4205153-A FLAME-RETARDANT ELASTOMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-05-27 US claimed
JP-63265922-A None JP disclosed
CN-117396782-A Optical laminate, polarizing plate, image display device, and method for manufacturing optical laminate 迪睿合株式会社 2024-01-12 CN disclosed
US-9591848-B2 Biofilm resistant polymer materials Abilene Christian Univ. (US) 2017-03-14 US disclosed
US-9591848-B2 Biofilm resistant polymer materials Abilene Christian Univ. (US) 2017-03-14 US disclosed
US-9591848-B2 Biofilm resistant polymer materials Abilene Christian Univ. (US) 2017-03-14 US disclosed
US-9072292-B2 Biofilm resistant polymer materials ABILENE CHRISTIAN UNIVERSITY 2015-07-07 US disclosed
US-9072292-B2 Biofilm resistant polymer materials ABILENE CHRISTIAN UNIVERSITY 2015-07-07 US disclosed
US-9072292-B2 Biofilm resistant polymer materials ABILENE CHRISTIAN UNIVERSITY 2015-07-07 US disclosed
US-20090047486-A1 LIGHT MANAGEMENT FILMS WITH ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2009-02-19 US disclosed
EP-1906265-A1 VOLUME PHASE HOLOGRAM RECORDING MATERIAL, PROCESS FOR PRODUCING THE SAME, AND RECORDED MATERIAL TOAGOSEI CO., LTD. (JP) 2008-04-02 EP disclosed
EP-1869509-A2 LIGHT MANAGEMENT FILMS WITH ZIRCONIA PARTICLES 3M Innovative Properties Company (US) 2007-12-26 EP disclosed
WO-2006098899-A2 LIGHT MANAGEMENT FILMS WITH ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-09-21 WO disclosed
US-20060204745-A1 Light management films with zirconia particles 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 US disclosed
JP-S63265922-A RESIN FOR PLASTIC LENS AND PLASTIC LENS COMPRISING SAME MITSUI TOATSU CHEM INC 1988-11-02 JP disclosed
US-4415704-A A THERMOPLASTIC RESIN WITH A HALOPHENYL ACRYLATE/BUTADIENE COPOLYMER; FIREPROOFING; CARPETS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-15 US disclosed
US-4205153-A FLAME-RETARDANT ELASTOMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090304621-A1 Biofilm Resistant Polymer Materials SELP, ICAM1, SLC11A2 MAPK1 4123/4885ALDH1A1 1310/4885TDP1 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.