Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134891 | 0.84 | RIPK1 (0.32) | MTNR1AKMT2A | |
| SCHEMBL30016207 | 0.76 | KMT2A (0.40) | MALT1HTR2AALDH1A1KMT2A | |
| SCHEMBL29134330 | 0.76 | KMT2A (0.40) | MALT1HTR2AALDH1A1KMT2A | |
| SCHEMBL30015645 | 0.76 | KMT2A (0.40) | MALT1HTR2AALDH1A1KMT2A | |
| SCHEMBL30015936 | 0.75 | PDE4A (0.39) | PIM1FAAHCNR2MAPTMTNR1A | |
| SCHEMBL29134358 | 0.75 | PDE4A (0.39) | PIM1FAAHCNR2MAPTMTNR1A | |
| SCHEMBL30015792 | 0.73 | HTR2A (0.38) | HTR2AHTR1A | |
| SCHEMBL29134906 | 0.70 | MTNR1A (0.37) | MTNR1A | |
| SCHEMBL17478440 | 0.67 | MALT1 (0.51) | MALT1MAPTMTNR1A | |
| SCHEMBL17478439 | 0.67 | MALT1 (0.51) | MALT1MAPTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |