Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134906 | 0.86 | MTNR1A (0.37) | RIPK1FPR2MTNR1AP2RX7 | |
| SCHEMBL29134323 | 0.84 | MALT1 (0.36) | KMT2AMTNR1A | |
| SCHEMBL29134330 | 0.76 | KMT2A (0.40) | KMT2AFFAR1NPSR1L3MBTL1 | |
| SCHEMBL30016207 | 0.76 | KMT2A (0.40) | KMT2AFFAR1NPSR1L3MBTL1 | |
| SCHEMBL29134815 | 0.76 | CA2 (0.32) | — | |
| SCHEMBL30015645 | 0.76 | KMT2A (0.40) | KMT2AFFAR1NPSR1L3MBTL1 | |
| SCHEMBL31120659 | 0.70 | — | — | |
| SCHEMBL31187873 | 0.69 | GAA (0.43) | — | |
| SCHEMBL31278084 | 0.68 | ALDH1A1 (0.46) | RIPK1 | |
| SCHEMBL31120631 | 0.67 | KDM1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |