Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.41 |
| ▸ | EDNRB | P24530 | 9/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721723 | 0.76 | ALDH1A1 (0.47) | EDNRAEDNRBHDAC4FABP5GID4 | |
| SCHEMBL12749373 | 0.73 | KDM1A (0.50) | EDNRAEDNRBFABP5 | |
| SCHEMBL1478222 | 0.73 | KDM1A (0.50) | EDNRAEDNRBFABP5 | |
| SCHEMBL16450274 | 0.73 | KDM1A (0.50) | EDNRAEDNRBFABP5 | |
| SCHEMBL16844584 | 0.72 | AGTR2 (0.47) | FABP5ALDH1A1 | |
| SCHEMBL16844583 | 0.72 | AGTR2 (0.47) | FABP5ALDH1A1 | |
| SCHEMBL16844599 | 0.72 | AGTR2 (0.47) | FABP5ALDH1A1 | |
| SCHEMBL1477468 | 0.71 | KDM1A (0.55) | EDNRAEDNRBHDAC4KDM4EPOLB | |
| SCHEMBL1477853 | 0.71 | KDM1A (0.55) | EDNRAEDNRBHDAC4KDM4EPOLB | |
| SCHEMBL1477851 | 0.71 | KDM1A (0.55) | EDNRAEDNRBHDAC4KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |