Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015692 | 1.00 | TDP1 (0.38) | TDP1KDM4ESMN1; SMN2TSHRGLA | |
| SCHEMBL13040418 | 1.00 | TDP1 (0.38) | TDP1KDM4ESMN1; SMN2TSHRGLA | |
| SCHEMBL30015975 | 1.00 | TDP1 (0.38) | TDP1KDM4ESMN1; SMN2TSHRGLA | |
| SCHEMBL13520272 | 0.79 | SMN1; SMN2 (0.38) | TDP1KDM4ESMN1; SMN2TSHRGLA | |
| SCHEMBL7379004 | 0.78 | CA12 (0.54) | ALDH1A1L3MBTL1GAAMEN1USP2 | |
| SCHEMBL7327209 | 0.78 | CA12 (0.54) | ALDH1A1L3MBTL1GAAMEN1USP2 | |
| SCHEMBL21760787 | 0.78 | ALDH1A1 (0.39) | TDP1KDM4ESMN1; SMN2TSHRGLA | |
| SCHEMBL11158533 | 0.77 | MAOB (0.48) | TDP1KDM4EALDH1A1MAPK1GAA | |
| SCHEMBL23663443 | 0.74 | THRB (0.41) | THRBALOX15APPTUBB4ATUBB | |
| SCHEMBL31426534 | 0.74 | DGAT1 (0.34) | SMN1; SMN2ALDH1A1GAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |