Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405521 | 0.81 | HSD17B10 (0.61) | HSD17B10POLBHTTMYCALOX15 | |
| SCHEMBL28484200 | 0.79 | ALDH1A1 (0.44) | L3MBTL1KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL28486433 | 0.76 | PDE2A (0.36) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28492642 | 0.75 | SLC6A2 (0.45) | KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL12089746 | 0.74 | NOTUM (0.55) | HSD17B10POLBHTTMYCALOX15 | |
| SCHEMBL2610310 | 0.74 | POLB (0.48) | HSD17B10POLBKDM4EALDH1A1RAPGEF4 | |
| SCHEMBL3987986 | 0.73 | KDM4E (0.55) | HSD17B10MYCALOX15PTPN7MEN1 | |
| SCHEMBL28025054 | 0.73 | MYC (0.45) | HSD17B10POLBHTTMYCALOX15 | |
| SCHEMBL30622485 | 0.73 | KDM4E (0.55) | HSD17B10MYCALOX15PTPN7MEN1 | |
| SCHEMBL24931088 | 0.72 | KDM4E (0.61) | HSD17B10POLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |