Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MYC | P01106 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332169 | 0.88 | HSD17B10 (0.57) | HSD17B10ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL12089746 | 0.87 | NOTUM (0.55) | HSD17B10ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL18950564 | 0.81 | HSD17B10 (0.54) | HSD17B10ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL29134576 | 0.81 | HSD17B10 (0.47) | HSD17B10ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL1664109 | 0.81 | ALDH1A1 (0.53) | HSD17B10ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL12094386 | 0.80 | HAO1 (0.55) | HSD17B10ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL11723689 | 0.78 | ALDH1A1 (0.44) | HSD17B10ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL3987986 | 0.77 | KDM4E (0.55) | HSD17B10ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL30622485 | 0.77 | KDM4E (0.55) | HSD17B10ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL28025054 | 0.77 | MYC (0.45) | HSD17B10ALDH1A1KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |