Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581098 | 0.82 | HDAC1 (0.62) | HDAC1HDAC3HDAC2MEN1KMT2A | |
| SCHEMBL31109034 | 0.76 | HDAC1 (0.56) | HDAC1HDAC3HDAC2MEN1KMT2A | |
| SCHEMBL25268984 | 0.74 | HDAC1 (0.55) | HDAC1HDAC3HDAC2MEN1KMT2A | |
| SCHEMBL330966 | 0.74 | PTPN1 (0.60) | ERN1 | |
| SCHEMBL2276911 | 0.74 | HDAC1 (0.73) | HDAC1HDAC3HDAC2PRSS12MEN1 | |
| SCHEMBL20442280 | 0.73 | KCNMA1 (0.64) | HDAC1KCNMA1NPC1LMNATP53 | |
| SCHEMBL845142 | 0.73 | LMNA (1.00) | KCNMA1NPC1LMNATP53GAA | |
| SCHEMBL29276645 | 0.73 | KCNMA1 (0.68) | HDAC1KCNMA1NPC1LMNATP53 | |
| SCHEMBL127201 | 0.73 | P2RX1 (0.63) | MEN1KMT2A | |
| SCHEMBL1318978 | 0.72 | HDAC1 (0.47) | HDAC1HDAC3HDAC2GAAPRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117045683-B | Cell therapy method for repairing spinal cord injury by using neural stem cells | 北京国卫生物科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117045680-B | Stem cell preparation for promoting liver regeneration and preparation method thereof | 北京国卫生物科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117045680-A | Stem cell preparation for promoting liver regeneration and preparation method thereof | 北京国卫生物科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-117045683-A | Novel cell therapy method for repairing spinal cord injury by using neural stem cells | 北京国卫生物科技有限公司 | 2023-11-14 | — | — | CN | disclosed |