SCHEMBL2913462

SCHEMBL2913462

CC(C)(C)c1cc(C(C)(C)c2ccc(O)c(C(C)(C)C)c2)ccc1O.CC(C)(c1ccc(O)c(C2CCCCC2)c1)c1ccc(O)c(C2CCCCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.43
NUDT1 P36639 1/20 0.43
BACE1 P56817 1/20 0.43
ATM Q13315 1/20 0.43
ALOX15 P16050 4/20 0.41
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 3/20 0.41
NR1I2 O75469 1/20 0.41
LMNA P02545 1/20 0.41
CYP2C9 P11712 1/20 0.41
MIF P14174 1/20 0.41
TYR P14679 1/20 0.41
HTT P42858 1/20 0.41
NFE2L2 Q16236 1/20 0.41
ESR1 P03372 1/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
CACNA1B Q00975 1/20 0.40
NR1H4 Q96RI1 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368513 0.91 NUDT1 (0.50) HSP90AA1NUDT1BACE1ALOX15ALDH1A1
SCHEMBL68186 0.91 NUDT1 (0.50) HSP90AA1NUDT1BACE1ALOX15ALDH1A1
SCHEMBL29623103 0.90 NUDT1 (0.49) HSP90AA1NUDT1BACE1ALOX15ALDH1A1
SCHEMBL13609954 0.90 NUDT1 (0.49) HSP90AA1NUDT1BACE1ALOX15ALDH1A1
SCHEMBL2913464 0.88 NUDT1 (0.44) HSP90AA1NUDT1BACE1ATMALOX15
SCHEMBL9720285 0.87 RORC (0.59) HSP90AA1NUDT1BACE1ATMALOX15
SCHEMBL2340495 0.85 ESR1 (0.49) HSP90AA1NUDT1BACE1ALOX15ALDH1A1
SCHEMBL17354422 0.85 NUDT1 (0.46) HSP90AA1NUDT1BACE1ALOX15ALDH1A1
SCHEMBL29458615 0.85 ESR1 (0.49) HSP90AA1NUDT1BACE1ALOX15ALDH1A1
SCHEMBL3133679 0.85 CYP2D6 (0.54) HSP90AA1NUDT1BACE1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655473-B1 METHOD FOR MAKING POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-07-06 EP disclosed
EP-1824899-B2 METHOD FOR MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP (NL) 2016-03-16 EP disclosed
EP-1597317-B1 TRANSLUCENT THERMOPLASTIC COMPOSITION, METHOD FOR MAKING THE COMPOSITION AND ARTICLES MOLDED THERE FROM. SABIC GLOBAL TECHNOLOGIES BV (NL) 2015-09-09 EP disclosed
EP-2655473-A1 METHOD FOR MAKING POLYCARBONATE SABIC Innovative Plastics IP B.V. (NL) 2013-10-30 EP disclosed
US-8263729-B2 Method for making polycarbonate SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-09-11 US disclosed
WO-2012085831-A1 METHOD FOR MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-06-28 WO disclosed
US-20120157639-A1 METHOD FOR MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-06-21 US disclosed
EP-1819750-B1 METHOD FOR MAKING POLYCARBONATES SABIC INNOVATIVE PLASTICS IP (NL) 2010-08-25 EP disclosed
EP-1824899-B1 METHOD FOR MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP (NL) 2010-02-17 EP disclosed
EP-2007829-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF Sabic Innovative Plastics IP B.V. (NL) 2008-12-31 EP disclosed
EP-0626410-A2 Method for making polycarbonates GENERAL ELECTRIC COMPANY (US) 1994-11-30 EP disclosed
EP-0626408-A2 A method for making polycarbonate substantially free of diaryl carbonate GENERAL ELECTRIC COMPANY (US) 1994-11-30 EP disclosed
EP-0626407-A2 Method for making flame retardant polycarbonate GENERAL ELECTRIC COMPANY (US) 1994-11-30 EP disclosed
US-5319066-A Method for making polycarbonates GENERAL ELECTRIC COMPANY (US) 1994-06-07 US disclosed
US-5300624-A Method for making flame retardant polycarbonate GENERAL ELECTRIC COMPANY (US) 1994-04-05 US disclosed
US-5214183-A Method for making oligomeric bisphenol monochloroformate polycarbonate oligomers and product GENERAL ELECTRIC COMPANY (US) 1993-05-25 US disclosed
EP-0477557-A2 Method for making cyclic oligomeric aromatic polycarbonates GENERAL ELECTRIC COMPANY (US) 1992-04-01 EP disclosed
EP-0456052-A2 A method for making end-capped polycarbonates from bisphenol monochloroformate polycarbonate oligomers GENERAL ELECTRIC COMPANY (US) 1991-11-13 EP disclosed
EP-0456053-A2 Method for making oligomeric bisphenol monochloroformate polycarbonate oligomers and product GENERAL ELECTRIC COMPANY (US) 1991-11-13 EP disclosed
US-5043203-A Method for making end-capped polycarbonates from bisphenol monochloroformate polycarbonate oligomers with pH control system GENERAL ELECTRIC COMPANY (US) 1991-08-27 US disclosed