Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.49 |
| ▸ | LPL | P06858 | 12/20 | 0.49 |
| ▸ | F11 | P03951 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237794 | 0.85 | ESR2 (0.50) | ESR2LIPGLPLF11F2 | |
| SCHEMBL31376528 | 0.85 | ESR2 (0.50) | ESR2LIPGLPLF11F2 | |
| SCHEMBL19996345 | 0.80 | LIPG (0.53) | ESR2LIPGLPLF11F2 | |
| SCHEMBL29185329 | 0.80 | ESR2 (0.49) | ESR2LIPGLPLF11F2 | |
| SCHEMBL24775237 | 0.79 | LIPG (0.52) | ESR2LIPGLPLF11F2 | |
| SCHEMBL24774874 | 0.79 | LIPG (0.52) | ESR2LIPGLPLF11F2 | |
| SCHEMBL14694622 | 0.79 | LIPG (0.52) | ESR2LIPGLPLF11F2 | |
| SCHEMBL15481251 | 0.78 | ESR2 (0.58) | ESR2LIPGLPLF11F2 | |
| SCHEMBL4508180 | 0.78 | LPL (0.50) | ESR2LIPGLPLF11F2 | |
| SCHEMBL3213609 | 0.78 | LPL (0.50) | ESR2LIPGLPLF11F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |