Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 9/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698052 | 1.00 | IGF1R (0.34) | IGF1RINSRHTR2CMEN1KMT2A | |
| SCHEMBL24698050 | 0.81 | IGF1R (0.41) | IGF1RINSRHTR2CKDM4EALDH1A1 | |
| SCHEMBL24699352 | 0.80 | BMPR1A (0.35) | IGF1RINSRMEN1KMT2AKDM4E | |
| SCHEMBL24698700 | 0.79 | MTOR (0.38) | KDM4E | |
| SCHEMBL30017019 | 0.79 | MTOR (0.38) | KDM4E | |
| SCHEMBL24699001 | 0.78 | MTOR (0.36) | IGF1RINSRMEN1KMT2AMAP3K12 | |
| SCHEMBL24698849 | 0.78 | KHK (0.39) | HTR2CMEN1KMT2AKHK | |
| SCHEMBL24699075 | 0.78 | KCNH2 (0.36) | MEN1KMT2AALDH1A1MAP3K12 | |
| SCHEMBL24697573 | 0.78 | P2RX7 (0.34) | MEN1KMT2AMAP3K12 | |
| SCHEMBL24699489 | 0.78 | GSK3B (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |