Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 12/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016360 | 1.00 | KEAP1 (0.63) | KEAP1NOTUMENPP2KDM4EALDH1A1 | |
| SCHEMBL14961974 | 0.82 | NOTUM (0.75) | KEAP1NOTUM | |
| SCHEMBL29134916 | 0.79 | NOTUM (0.58) | KEAP1NOTUMENPP2 | |
| SCHEMBL552775 | 0.78 | LMNA (0.47) | NOTUMENPP2KDM4EALDH1A1MGLL | |
| SCHEMBL21776982 | 0.77 | KEAP1 (1.00) | KEAP1NOTUMMGLL | |
| SCHEMBL11410355 | 0.77 | NOTUM (0.64) | KEAP1NOTUMALDH1A1 | |
| SCHEMBL21152131 | 0.77 | LMNA (0.55) | NOTUM | |
| Hydrochloric Acid SCHEMBL31245632 | 0.76 | NOTUM (0.62) | KEAP1NOTUMALDH1A1 | |
| SCHEMBL670667 | 0.74 | NOTUM (0.65) | KEAP1NOTUMALDH1A1MGLL | |
| SCHEMBL3156314 | 0.74 | NOTUM (0.64) | KEAP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |