SCHEMBL2731932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18431359	0.81	AR (0.54)	ARMAOAMAOBDHFRKMT2A
	SCHEMBL14712743	0.81	MAOB (0.56)	ARMAOAMAOBDHFRPOLB
	SCHEMBL3289071	0.80	AR (0.56)	ARPTGIRDHFRKMT2AHAO1
	SCHEMBL13729942	0.80	MAOA (0.50)	ARMAOAMAOBDHFR
	SCHEMBL31345522	0.79	AR (0.55)	ARPTGIRDHFRKMT2AHAO1
	SCHEMBL2887154	0.79	AR (0.55)	ARPTGIRDHFRKMT2AHAO1
	SCHEMBL29134917	0.78	MAOB (0.56)	ARMAOAMAOBPTGIRL3MBTL1
	SCHEMBL23720058	0.77	AR (0.54)	ARPTGIRDHFRKMT2AHAO1
	SCHEMBL5688223	0.77	AR (0.54)	ARPTGIRDHFRKMT2AHAO1
	SCHEMBL15418635	0.77	AR (0.54)	ARPTGIRDHFRKMT2AHAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.