Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199231 | 0.78 | MAPK1 (0.56) | MAPTMAPK1TDP1L3MBTL1MAPK14 | |
| SCHEMBL1013987 | 0.77 | PTGER1 (0.44) | MAPTMAPK1TDP1L3MBTL1MAPK14 | |
| SCHEMBL28901193 | 0.76 | ROCK1 (0.65) | MAPTMAPK1TDP1L3MBTL1ROCK1 | |
| SCHEMBL28487163 | 0.75 | VCP (0.40) | MAPK1L3MBTL1VCPPLAUHTT | |
| SCHEMBL29134579 | 0.73 | VCP (0.42) | MAPTL3MBTL1VCPMAPK14BRD4 | |
| SCHEMBL20337868 | 0.71 | CSF1R (0.49) | MAPTMAPK1TDP1L3MBTL1BRD4 | |
| SCHEMBL29134588 | 0.70 | KDM4E (0.41) | MAPTVCPMAPK14 | |
| SCHEMBL769005 | 0.69 | RHEB (0.55) | MAPTMAPK1TDP1L3MBTL1ROCK1 | |
| SCHEMBL1563544 | 0.69 | LTA4H (0.64) | MAPTMAPK1TDP1L3MBTL1MAPK14 | |
| SCHEMBL28492642 | 0.69 | SLC6A2 (0.45) | MAPTVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |