Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134590 | 0.82 | CYP17A1 (0.41) | KDM4EALDH1A1HPGDMAPK14VCP | |
| SCHEMBL29387435 | 0.74 | SMN1; SMN2 (0.43) | KDM4EALDH1A1HPGDMAPK14PDCD1 | |
| SCHEMBL4865308 | 0.74 | SMN1; SMN2 (0.43) | KDM4EALDH1A1HPGDMAPK14PDCD1 | |
| SCHEMBL29134981 | 0.72 | RAB9A (0.43) | KDM4EALDH1A1HPGDPDCD1CD274 | |
| SCHEMBL29134982 | 0.72 | PDE10A (0.45) | KDM4EALDH1A1HPGDPDCD1CD274 | |
| SCHEMBL30704294 | 0.72 | PDE10A (0.45) | KDM4EALDH1A1HPGDPDCD1CD274 | |
| SCHEMBL25587417 | 0.72 | HTR2A (0.38) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL4872843 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDACHE | |
| SCHEMBL434299 | 0.71 | CYP19A1 (0.46) | KDM4EALDH1A1HSD17B10HPGDFNTA | |
| SCHEMBL15063446 | 0.70 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10HPGDPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |