Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704294 | 1.00 | PDE10A (0.45) | PDE10ARAB9APTK2SLC11A2CYP1A2 | |
| SCHEMBL29134981 | 0.89 | RAB9A (0.43) | PDE10ARAB9APTK2SLC11A2CYP1A2 | |
| SCHEMBL29387435 | 0.81 | SMN1; SMN2 (0.43) | RAB9ACYP1A2KDM4EALDH1A1MEN1 | |
| SCHEMBL4865308 | 0.81 | SMN1; SMN2 (0.43) | RAB9ACYP1A2KDM4EALDH1A1MEN1 | |
| SCHEMBL30704300 | 0.80 | MAPK14 (0.40) | SLC11A2CYP1A2KDM4EALDH1A1MEN1 | |
| SCHEMBL30704311 | 0.80 | MAT2A (0.50) | CYP1A2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29134984 | 0.80 | MAT2A (0.50) | CYP1A2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29134581 | 0.80 | MAPK14 (0.40) | SLC11A2CYP1A2KDM4EALDH1A1MEN1 | |
| SCHEMBL4872843 | 0.80 | KDM4E (0.51) | PDE10ARAB9ASLC11A2KDM4EALDH1A1 | |
| SCHEMBL19329879 | 0.78 | PDE10A (0.44) | PDE10ARAB9AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |