Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134731 | 0.91 | GAA (0.61) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| Thiophene Carboxylic Acid SCHEMBL29135071 | 0.85 | KMT2A (0.69) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL23559189 | 0.80 | KMT2A (0.81) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29134713 | 0.79 | NR3C1 (0.55) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29134720 | 0.75 | NR3C1 (0.61) | MAPTLMNASMN1; SMN2GAACYP3A4 | |
| Thiophene Carboxylic Acid SCHEMBL29135074 | 0.75 | AKR1C3 (0.70) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29134739 | 0.74 | KMT2A (0.70) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29134717 | 0.73 | TSHR (0.60) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29134725 | 0.73 | KMT2A (0.65) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL664021 | 0.72 | KMT2A (1.00) | KMT2AMEN1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | disclosed |