Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene Carboxylic Acid SCHEMBL29135074 | 0.89 | AKR1C3 (0.70) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL23559189 | 0.87 | KMT2A (0.81) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29134725 | 0.85 | KMT2A (0.65) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29134739 | 0.85 | KMT2A (0.70) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29135067 | 0.85 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL664021 | 0.82 | KMT2A (1.00) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29135069 | 0.80 | KMT2A (0.69) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| Benzoic Acid SCHEMBL29134718 | 0.77 | AKR1C3 (0.84) | KMT2AMEN1SMN1; SMN2LMNAAKR1C3 | |
| SCHEMBL665198 | 0.77 | MEN1 (0.87) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29134741 | 0.75 | MEN1 (0.73) | KMT2AMEN1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | disclosed |