Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 5/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690142 | 0.87 | DRD2 (0.41) | HTR3ATRPA1ALDH1A1MAOB | |
| SCHEMBL15081288 | 0.78 | MAPT (0.40) | FAAHCYP3A4ALDH1A1MAPTTDP1 | |
| SCHEMBL18063609 | 0.78 | MEN1 (0.45) | FAAHALDH1A1MAPT | |
| SCHEMBL5618227 | 0.77 | FAAH (0.41) | FAAHHTR3AMGLL | |
| SCHEMBL12209283 | 0.77 | GRM4 (0.49) | SCDHTR3ACYP1A2ALDH1A1MAPT | |
| SCHEMBL8945044 | 0.77 | FAAH (0.36) | FAAHSCDHTR3AMGLL | |
| SCHEMBL30716972 | 0.77 | GRM4 (0.49) | SCDHTR3ACYP1A2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6993663 | 0.76 | FAAH (0.40) | FAAHHTR3AMGLL | |
| SCHEMBL21257487 | 0.75 | CSNK2A2 (0.41) | FAAHTRPA1ALDH1A1MAPTMGLL | |
| SCHEMBL8142563 | 0.75 | FAAH (0.56) | FAAHCYP1A2CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304204-A | Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-12-29 | — | — | CN | disclosed |