Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 3/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945012 | 0.83 | FAAH (0.50) | FAAHMGLLAAK1SSTR4HTR3A | |
| Hydrochloric Acid SCHEMBL8945446 | 0.82 | FAAH (0.49) | FAAHMGLLAAK1SSTR4HTR3A | |
| SCHEMBL8945315 | 0.80 | FAAH (0.56) | FAAHMGLLSSTR4 | |
| Hydrochloric Acid SCHEMBL8945205 | 0.78 | FAAH (0.55) | FAAHMGLLSSTR4 | |
| SCHEMBL5618227 | 0.78 | FAAH (0.41) | FAAHMGLLHTR3A | |
| SCHEMBL8944946 | 0.78 | FAAH (0.43) | FAAHMGLLSSTR4 | |
| Hydrochloric Acid SCHEMBL6993663 | 0.77 | FAAH (0.40) | FAAHMGLLHTR3A | |
| SCHEMBL29135587 | 0.77 | FAAH (0.40) | FAAHMGLLSCDHTR3A | |
| SCHEMBL8945338 | 0.76 | L3MBTL1 (0.46) | — | |
| SCHEMBL8945129 | 0.72 | FAAH (0.36) | FAAHMGLLSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |