SCHEMBL29135908

SCHEMBL29135908

CCCCCCCCCCCCNCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.45
ESR1 P03372 7/20 0.40
DRD2 P14416 3/20 0.38
DRD4 P21917 3/20 0.38
DRD3 P35462 3/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.36
NAAA Q02083 1/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31682488 0.94 KDM4E (0.41) SIGMAR1DRD2DRD4DRD3KDM4E
SCHEMBL29839764 0.91 EPHX2 (0.40) SIGMAR1CNR1CNR2
SCHEMBL20954569 0.90 SIGMAR1 (0.43) SIGMAR1DRD2DRD4DRD3CNR1
SCHEMBL10175239 0.88 HTR1B (0.40) SIGMAR1DRD2DRD4DRD3HTT
SCHEMBL554231 0.88 HTT (0.41) DRD2DRD4DRD3HTT
SCHEMBL4398294 0.86 ALDH1A1 (0.42) ESR1DRD2DRD4DRD3KDM4E
SCHEMBL15426891 0.85 SOAT1 (0.41) ESR1DRD2DRD3CNR1ALDH1A1
SCHEMBL13284463 0.85 SOAT1 (0.41) ESR1DRD2DRD3CNR1ALDH1A1
SCHEMBL16888352 0.85 SOAT1 (0.41) ESR1DRD2DRD3CNR1ALDH1A1
SCHEMBL18724647 0.85 SOAT1 (0.41) ESR1DRD2DRD3CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025228979-A1 LIPIDS NANOPARTICLE FORMULATIONS SUITABLE FOR LUNG TARGETING NEOVAC LTD. (GB) 2025-11-06 WO disclosed
EP-4288104-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY Ramot at Tel-Aviv University Ltd. (IL) 2023-12-13 EP disclosed
CN-117136074-A Lipids suitable for nucleic acid delivery 雷蒙特亚特特拉维夫大学有限公司 2023-11-28 CN disclosed
WO-2022168085-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-08-11 WO disclosed