Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | USP7 | Q93009 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
| ▸ | GRK1 | Q15835 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656549 | 1.00 | IDO1 (0.51) | IDO1USP7MRGPRX4MMP13GRK2 | |
| SCHEMBL29778919 | 0.87 | YTHDC1 (0.50) | IDO1USP7MMP13GRK2RAB9A | |
| SCHEMBL24617509 | 0.87 | YTHDC1 (0.50) | IDO1USP7MMP13GRK2RAB9A | |
| SCHEMBL29779016 | 0.87 | IDO1 (0.54) | IDO1USP7MMP13SLC2A1SMN1; SMN2 | |
| SCHEMBL1500346 | 0.85 | GRK2 (0.60) | USP7MMP13GRK2GRK1RAB9A | |
| SCHEMBL17502553 | 0.84 | MMP13 (0.58) | MMP13GRK2 | |
| SCHEMBL24617406 | 0.80 | ROCK2 (0.62) | MMP13GRK2 | |
| SCHEMBL29778896 | 0.80 | ROCK2 (0.62) | MMP13GRK2 | |
| SCHEMBL29136019 | 0.79 | KMT2A (0.45) | IDO1MRGPRX4 | |
| SCHEMBL30656512 | 0.79 | KMT2A (0.45) | IDO1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136186-A | Selective inhibitors of ROCK1 and ROCK2 protein kinases and uses thereof | 盖诺斯克公司 | 2023-11-28 | — | — | CN | disclosed |