SCHEMBL29136047

SCHEMBL29136047

N[C@H](C(=O)O)c1cccc(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
HSD17B10 Q99714 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
CYP2C9 P11712 3/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2D6 P10635 1/20 0.50
ACP3 P15309 1/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
DRD3 P35462 1/20 0.50
GRM4 Q14833 1/20 0.50
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 4/20 0.47
GRM1 Q13255 3/20 0.47
GRM2 Q14416 2/20 0.47
PARP1 P09874 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29779063 1.00 MEN1 (0.51) MEN1KMT2AHSD17B10TDP1CYP2C9
SCHEMBL29454480 1.00 MEN1 (0.51) MEN1KMT2AHSD17B10TDP1CYP2C9
SCHEMBL3623486 1.00 MEN1 (0.51) MEN1KMT2AHSD17B10TDP1CYP2C9
SCHEMBL27865867 1.00 MEN1 (0.51) MEN1KMT2AHSD17B10TDP1CYP2C9
Hydrochloric Acid SCHEMBL30049630 0.98 MEN1 (0.50) MEN1KMT2AHSD17B10TDP1CYP2C9
Phenylglycine SCHEMBL28274995 0.91 MEN1 (0.50) MEN1KMT2AHSD17B10TDP1CYP2C9
SCHEMBL1353575 0.85 PARP1 (0.50) MEN1KMT2AACP3PARP1
SCHEMBL1353577 0.85 PARP1 (0.50) MEN1KMT2AACP3PARP1
SCHEMBL3320904 0.82 MEN1 (0.54) MEN1KMT2ATDP1ACP3PARP1
SCHEMBL30057642 0.81 FFAR1 (0.52) MEN1KMT2AHSD17B10TDP1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR UNIV CALIFORNIA (US) 2026-03-26 US disclosed
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-02 US disclosed
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-03 US disclosed
CN-118765276-A Deuterated compound, preparation method and application thereof 甘李药业股份有限公司 2024-10-11 CN disclosed
CN-117136186-A Selective inhibitors of ROCK1 and ROCK2 protein kinases and uses thereof 盖诺斯克公司 2023-11-28 CN disclosed
US-20230346960-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-11-02 US disclosed
US-11612663-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-28 US disclosed
US-20220313867-A1 ENGINEERED SCAFFOLDS FOR VASCULARIZED TISSUE REPAIR THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346960-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR PDGFA, PDGFRB, TEK MEN1 4811/4885KMT2A 4334/4885HSD17B10 3339/4885
US-20220313867-A1 ENGINEERED SCAFFOLDS FOR VASCULARIZED TISSUE REPAIR FLT4, FLT1, KDR MEN1 2992/4885KMT2A 4128/4885HSD17B10 2756/4885
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair PDGFA, PDGFRB, TEK MEN1 4811/4885KMT2A 4334/4885HSD17B10 3339/4885
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR PDGFA, DCLRE1A, PDGFRA MEN1 4697/4885KMT2A 2690/4885HSD17B10 4113/4885
US-11612663-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair PDGFA, PDGFRB, TEK MEN1 4811/4885KMT2A 4334/4885HSD17B10 3339/4885
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells ITGB4, ITGA4, ITGB1 MEN1 1806/4885KMT2A 3524/4885HSD17B10 4210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.