Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 19/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16679369 | 0.88 | L3MBTL1 (0.50) | MAPK1 | |
| SCHEMBL16679365 | 0.88 | L3MBTL1 (0.50) | MAPK1 | |
| SCHEMBL16679977 | 0.87 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL16679979 | 0.87 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL29136028 | 0.83 | KEAP1 (0.56) | — | |
| SCHEMBL29136031 | 0.83 | KEAP1 (0.56) | — | |
| SCHEMBL30656440 | 0.81 | MAPK1 (0.50) | DCAF1MAPK1 | |
| SCHEMBL29136051 | 0.81 | MAPK1 (0.50) | DCAF1MAPK1 | |
| SCHEMBL19025632 | 0.76 | ALDH1A1 (0.56) | DCAF1MAPK1 | |
| SCHEMBL28076662 | 0.76 | ALDH1A1 (0.56) | DCAF1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136186-A | Selective inhibitors of ROCK1 and ROCK2 protein kinases and uses thereof | 盖诺斯克公司 | 2023-11-28 | — | — | CN | disclosed |