Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140883 | 0.82 | CYP1A2 (0.40) | PLCG1CYP1A2MMP2MMP1MMP9 | |
| SCHEMBL3129668 | 0.79 | FPR2 (0.41) | CYP1A2MMP2CA2CA1MMP9 | |
| SCHEMBL5159231 | 0.79 | SRC (0.55) | SRCKMT2A | |
| SCHEMBL27446921 | 0.78 | SRC (0.53) | SRCKMT2A | |
| SCHEMBL28726302 | 0.74 | RPLP1 (0.50) | MMP2CA2CA1MMP1MMP9 | |
| SCHEMBL5049918 | 0.72 | EGFR (0.45) | KMT2A | |
| SCHEMBL3134984 | 0.71 | CYP1A2 (0.44) | CYP1A2MMP2CA2CA1MMP1 | |
| SCHEMBL3616092 | 0.71 | CYP1A2 (0.39) | PLCG1CYP1A2SRCMMP2CA2 | |
| SCHEMBL6676227 | 0.70 | KMT2A (0.50) | SRCKMT2A | |
| SCHEMBL31135530 | 0.69 | KMT2A (0.54) | CYP1A2KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |