Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140488 | 1.00 | KMT2A (0.54) | KMT2ACYP2C19LDHACYP1A2CNR2 | |
| SCHEMBL25377657 | 0.82 | KMT2A (0.53) | KMT2ACYP2C19CYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL6766 | 0.82 | KMT2A (0.53) | KMT2ACYP2C19CYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL9468277 | 0.82 | KMT2A (0.61) | KMT2ACYP2C19LDHACYP1A2CNR2 | |
| SCHEMBL5370872 | 0.82 | KMT2A (0.53) | KMT2ACYP2C19LDHACYP1A2CNR2 | |
| SCHEMBL7087165 | 0.81 | ESR1 (0.48) | KMT2ACYP2C19CYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL25293414 | 0.81 | PTGS1 (0.44) | KMT2ACYP2C19L3MBTL1ALDH1A1GAA | |
| SCHEMBL4198436 | 0.80 | CYP2C19 (0.59) | KMT2ACYP2C19POLBSMN1; SMN2MEN1 | |
| SCHEMBL3689059 | 0.80 | CYP2C19 (0.59) | KMT2ACYP2C19POLBSMN1; SMN2MEN1 | |
| SCHEMBL468727 | 0.80 | CYP2C19 (0.59) | KMT2ACYP2C19POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145561-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | RESEARCH TRIANGLE INSTITUTE (US) | 2025-05-08 | — | — | US | disclosed |
| CN-118541348-A | 4-Substituted-phenylacetamides and aryl ureas as agonists of the orphan receptor GPR88 | 研究三角协会 | 2024-08-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145561-A1 | 4-SUBSTITUTED-PHENYL ACETAMIDES AND ARYLUREAS AS AGONISTS FOR THE ORPHAN RECEPTOR GPR88 | GPR88, GPR84, GPR139 | KMT2A 823/4885CYP2C19 1721/4885LDHA 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.