SCHEMBL29136385

SCHEMBL29136385

O=[N+]([O-])c1c(-c2ccccc2)cc(F)c(Cl)c1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.49
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
PTGES O14684 1/20 0.39
TSHR P16473 1/20 0.39
MAPT P10636 1/20 0.39
MEN1 O00255 1/20 0.39
PSMD14 O00487 1/20 0.39
PRKACA P17612 1/20 0.39
CASP6 P55212 1/20 0.39
KMT2A Q03164 1/20 0.39
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
HCRTR1 O43613 1/20 0.38
PKM P14618 1/20 0.38
CDK2 P24941 1/20 0.37
CYP2A6 P11509 1/20 0.37
POLB P06746 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28871473 0.89 HPRT1 (0.48) HPRT1ALDH1A1TDP1PTGESTSHR
SCHEMBL10975392 0.83 HPRT1 (0.51) HPRT1ALDH1A1TDP1TSHRMAPT
SCHEMBL29406174 0.80 HPRT1 (0.51) HPRT1ALDH1A1TDP1PTGESTSHR
SCHEMBL27979563 0.80 HPRT1 (0.51) HPRT1ALDH1A1TDP1PTGESTSHR
SCHEMBL2234399 0.76 ALDH1A1 (0.53) HPRT1ALDH1A1TDP1PTGESMAPT
SCHEMBL28045669 0.75 ALDH1A1 (0.47) HPRT1ALDH1A1TDP1TSHRMAPT
SCHEMBL9747267 0.73 HPRT1 (0.80) HPRT1ALDH1A1TDP1MEN1PSMD14
SCHEMBL1767571 0.73 ALDH1A1 (0.63) HPRT1ALDH1A1TDP1TSHRMEN1
SCHEMBL4583260 0.73 ALDH1A1 (0.53) HPRT1ALDH1A1TDP1TSHRMAPT
SCHEMBL17915595 0.73 ALDH1A1 (0.58) HPRT1ALDH1A1TDP1PTGESMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117321029-A Method for preparing substituted biphenyls via Suzuki coupling of aryl chlorides 巴斯夫欧洲公司 2023-12-29 CN disclosed