Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136401 | 1.00 | HCRTR1 (0.38) | HCRTR1HCRTR2RIPK1PRCP | |
| SCHEMBL24733173 | 0.86 | ALDH1A1 (0.43) | — | |
| SCHEMBL1914149 | 0.83 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL13505317 | 0.82 | HCRTR1 (0.37) | HCRTR1HCRTR2PRCP | |
| SCHEMBL1293417 | 0.82 | HCRTR1 (0.37) | HCRTR1HCRTR2PRCP | |
| SCHEMBL9980544 | 0.77 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL9980523 | 0.74 | HCRTR1 (0.39) | HCRTR1HCRTR2PRCP | |
| SCHEMBL18815238 | 0.74 | OPRD1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL18815239 | 0.74 | OPRD1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL1294005 | 0.73 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321059-A | Tetracyclic compounds for the treatment of Zika virus infection | 吉利德科学公司 | 2023-12-29 | — | — | CN | disclosed |