Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815239 | 0.86 | OPRD1 (0.40) | HCRTR1HCRTR2OPRD1 | |
| SCHEMBL18815238 | 0.86 | OPRD1 (0.40) | HCRTR1HCRTR2OPRD1 | |
| SCHEMBL13505317 | 0.86 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL1293417 | 0.86 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL1914149 | 0.83 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL15367045 | 0.83 | ALDH1A1 (0.47) | — | |
| SCHEMBL12066763 | 0.83 | ALDH1A1 (0.47) | — | |
| SCHEMBL9980505 | 0.80 | PRCP (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL9980523 | 0.80 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL29136404 | 0.77 | HCRTR1 (0.38) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575475-A1 | INHIBITORS OF HCV NS5A | Presidio Pharmaceuticals, Inc. (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011150243-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2011-12-01 | — | — | WO | disclosed |