Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136473 | 0.91 | LMNA (0.74) | LMNAHPGDL3MBTL1TDP1RAB9A | |
| SCHEMBL20604717 | 0.88 | SMN1; SMN2 (0.57) | LMNAHPGDL3MBTL1KMT2AHTT | |
| SCHEMBL18397048 | 0.87 | HPGD (0.82) | LMNAHPGDKMT2ATPMTSMN1; SMN2 | |
| SCHEMBL17844325 | 0.82 | HPGD (0.57) | LMNAHPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL17844306 | 0.82 | NPC1 (0.59) | LMNAHPGDKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9142765 | 0.81 | PDE4A (0.50) | LMNAHPGDL3MBTL1KMT2AHTT | |
| SCHEMBL24983425 | 0.80 | HPGD (0.84) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30892445 | 0.80 | HPGD (0.84) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5240840 | 0.80 | HPGD (0.74) | LMNAHPGDKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL21738207 | 0.79 | HPGD (0.77) | LMNAHPGDKMT2ATPMTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362192-A | PET radioactive tracer for imaging glycine transporter Glyt2 | 浙江颐核医疗科技有限公司 | 2024-01-09 | — | — | CN | disclosed |