Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136465 | 0.91 | LMNA (0.61) | LMNAHPGDL3MBTL1TDP1RAB9A | |
| SCHEMBL16250484 | 0.85 | LMNA (1.00) | LMNAHPGDL3MBTL1XDHKDM4E | |
| SCHEMBL17844325 | 0.85 | HPGD (0.57) | LMNAHPGDL3MBTL1XDHALDH1A1 | |
| SCHEMBL20604717 | 0.80 | SMN1; SMN2 (0.57) | LMNAHPGDL3MBTL1KDM4ETDP1 | |
| SCHEMBL4361298 | 0.79 | MAPT (0.77) | L3MBTL1KDM4ENFKB1NFKB2RELA | |
| SCHEMBL22430965 | 0.79 | HPGD (0.47) | LMNAHPGDL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL24983425 | 0.77 | HPGD (0.84) | LMNAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL30892445 | 0.77 | HPGD (0.84) | LMNAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL9325175 | 0.77 | KMT2A (0.55) | LMNAHPGDGAAALDH1A1MGLL | |
| SCHEMBL3110625 | 0.76 | LMNA (0.56) | LMNAHPGDL3MBTL1XDHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362192-A | PET radioactive tracer for imaging glycine transporter Glyt2 | 浙江颐核医疗科技有限公司 | 2024-01-09 | — | — | CN | disclosed |