Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | BTD | P43251 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3152387 | 1.00 | TSHR (0.34) | TSHRSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL20702398 | 1.00 | TSHR (0.34) | TSHRSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL4096660 | 0.89 | LMNA (0.42) | TSHRSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL1006759 | 0.88 | TSHR (0.36) | TSHRSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL27918028 | 0.87 | VNN1 (0.38) | SMN1; SMN2MAPK1ALDH1A1LMNAVNN1 | |
| SCHEMBL27772486 | 0.86 | CNR2 (0.38) | TSHRSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL12662817 | 0.84 | SMN1; SMN2 (0.38) | TSHRSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL30793840 | 0.84 | DPP4 (0.32) | TSHRSMN1; SMN2MAPK1DPP4 | |
| SCHEMBL16239742 | 0.83 | RBP4 (0.32) | TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL22183283 | 0.82 | DPP4 (0.34) | TSHRSMN1; SMN2MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417635-B | Pyrazolopyrimidines with anti-Respiratory Syncytial Virus (RSV) activity | 爱尔兰詹森科学公司 | 2024-01-02 | — | — | CN | disclosed |