Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033928 | 0.90 | KLKB1 (0.33) | GRM5KLKB1MAPT | |
| SCHEMBL29136933 | 0.83 | GRM5 (0.31) | GRM5KLKB1 | |
| SCHEMBL29137027 | 0.81 | KLKB1 (0.33) | GRM5KLKB1 | |
| SCHEMBL27033666 | 0.79 | GRM5 (0.33) | GRM5KLKB1 | |
| SCHEMBL24737346 | 0.76 | CA1 (0.39) | KLKB1 | |
| SCHEMBL21355124 | 0.76 | SUV39H2 (0.32) | KLKB1 | |
| SCHEMBL21355696 | 0.75 | CYP4F2 (0.35) | KLKB1MAPT | |
| SCHEMBL27033822 | 0.75 | KDM4E (0.33) | GRM5KLKB1MAPT | |
| SCHEMBL29137034 | 0.74 | METTL3 (0.47) | KLKB1 | |
| SCHEMBL21355085 | 0.74 | KLKB1 (0.47) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |