Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137314 | 0.89 | AAK1 (0.36) | BACE1 | |
| SCHEMBL29137313 | 0.87 | LMNA (0.36) | ALDH1A1HCRTR1HCRTR2POLBEGFR | |
| SCHEMBL29137242 | 0.83 | POLB (0.47) | MEN1ALDH1A1KMT2APOLBTDP2 | |
| SCHEMBL29137259 | 0.83 | HDAC1 (0.37) | ALDH1A1MAPTBRD2 | |
| SCHEMBL29137320 | 0.83 | TSHR (0.40) | POLBPARP10PARP11TSHRSMN1; SMN2 | |
| SCHEMBL29137345 | 0.81 | TUBB4A (0.32) | POLB | |
| SCHEMBL29137298 | 0.81 | POLB (0.37) | MEN1ALDH1A1KMT2APOLBTDP2 | |
| SCHEMBL29137223 | 0.81 | SMN1; SMN2 (0.34) | MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL29137252 | 0.81 | TDP2 (0.37) | MEN1ALDH1A1KMT2APOLBTDP2 | |
| SCHEMBL29137336 | 0.81 | KDM4E (0.36) | ALDH1A1TDP2BACE1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117326923-A | Fluorine-containing dihydronaphthalenone derivative and preparation method and application thereof | 上海应用技术大学 | 2024-01-02 | — | — | CN | disclosed |