Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137729 | 0.81 | APP (0.46) | MAPK1KMT2AMEN1LMNAMAPT | |
| SCHEMBL1747739 | 0.81 | POLB (0.43) | PTGS1PTGS2HPGDMAPK1MT-CO2 | |
| SCHEMBL27832415 | 0.80 | FFAR2 (0.33) | MAPK1KMT2AL3MBTL1LMNAMAPT | |
| SCHEMBL30768172 | 0.79 | PTGS2 (0.42) | PTGS1PTGS2HPGDMAPK1KMT2A | |
| SCHEMBL10666788 | 0.75 | MT-CO2 (0.46) | PTGS1PTGS2HPGDMT-CO2KMT2A | |
| SCHEMBL6640497 | 0.75 | KMT2A (0.49) | HPGDMAPK1KMT2AL3MBTL1MEN1 | |
| SCHEMBL21373757 | 0.75 | MAPK1 (0.37) | MAPK1MT-CO2KMT2AL3MBTL1MEN1 | |
| SCHEMBL25295103 | 0.74 | HPGD (0.41) | PTGS1PTGS2HPGDMT-CO2KMT2A | |
| SCHEMBL12844717 | 0.74 | HPGD (0.41) | PTGS1PTGS2HPGDMT-CO2KMT2A | |
| SCHEMBL30489970 | 0.74 | HPGD (0.41) | PTGS1PTGS2HPGDMT-CO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384153-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |