Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 5/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32661546 | 0.93 | ACACB (0.37) | MEN1NPC1RAB9AKMT2AACACB | |
| SCHEMBL29137720 | 0.85 | EZH2 (0.55) | MEN1NPC1RAB9AKMT2AACACB | |
| SCHEMBL29137721 | 0.78 | CAMK2D (0.40) | VNN1BRAFHDAC3HDAC1HDAC6 | |
| SCHEMBL32661517 | 0.75 | AURKA (0.34) | MEN1NPC1RAB9AKMT2ABRAF | |
| SCHEMBL32662613 | 0.74 | BRD4 (0.42) | MAPTNPSR1L3MBTL1HDAC1PIM1 | |
| SCHEMBL31563705 | 0.74 | BRD4 (0.42) | MAPTNPSR1L3MBTL1HDAC1PIM1 | |
| SCHEMBL29137722 | 0.72 | BRAF (0.39) | VNN1BRAFHDAC3HDAC1HDAC6 | |
| SCHEMBL29137730 | 0.72 | ROCK2 (0.40) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL30670498 | 0.72 | KDR (0.50) | MEN1NPC1RAB9AKMT2ABRAF | |
| SCHEMBL30768169 | 0.70 | NPC1 (0.41) | MEN1NPC1RAB9AKMT2ABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015352-A1 | METHYLTRANSFERASE INHIBITOR AND USE THEREOF | CYTOSINLAB THERAPEUTICS CO LTD (CN) | 2026-01-15 | — | — | US | disclosed |
| WO-2024012461-A1 | METHYLTRANSFERASE INHIBITOR AND USE THEREOF | 上海赛岚生物科技有限公司 | 2024-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015352-A1 | METHYLTRANSFERASE INHIBITOR AND USE THEREOF | EZH2, DOT1L, EHMT1 | MEN1 2466/4885NPC1 1396/4885RAB9A 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.