Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127411 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29471996 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12301533 | 0.84 | SLC7A5 (0.65) | SLC7A5LOXL2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21311029 | 0.84 | EGFR (0.53) | SLC7A5CYP4F2CYP4A11KDM4E | |
| SCHEMBL7384982 | 0.83 | SLC7A5 (0.63) | SLC7A5LOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL165622 | 0.83 | LOXL2 (0.66) | SLC7A5LOXL2CYP4F2CYP4A11MEP1B | |
| SCHEMBL3499880 | 0.83 | SLC7A5 (0.63) | SLC7A5LOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL18195638 | 0.82 | MEP1B (0.48) | SLC7A5LOXL2CYP4F2CYP4A11MEP1B | |
| SCHEMBL27989651 | 0.81 | LOXL2 (0.47) | SLC7A5LOXL2CYP4F2CYP4A11MEP1B | |
| SCHEMBL1246082 | 0.81 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605404-B | Novel thiazole-containing compound, intermediate and application thereof | 合肥美诺医药有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-114605404-A | Novel thiazole-containing compound, intermediate and application thereof | 苏州美诺医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |