Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397052 | 0.84 | NOS1 (0.37) | NOS1AXLBACE1AHRENPP3 | |
| SCHEMBL212027 | 0.76 | MAPT (0.35) | LMNA | |
| SCHEMBL2357116 | 0.76 | ALDH1A1 (0.45) | SMN1; SMN2 | |
| SCHEMBL7470262 | 0.73 | ALDH1A1 (0.50) | LMNASMN1; SMN2 | |
| SCHEMBL24690 | 0.72 | CCR1 (0.52) | LMNASMN1; SMN2 | |
| SCHEMBL29142758 | 0.72 | GRM5 (0.30) | GRM5 | |
| SCHEMBL659473 | 0.70 | NOS1 (0.42) | NOS1AXLBACE1AHRLMNA | |
| SCHEMBL29548266 | 0.70 | NOS1 (0.42) | NOS1AXLBACE1AHRLMNA | |
| SCHEMBL4854082 | 0.69 | ALDH1A1 (0.53) | NOS1SMN1; SMN2 | |
| SCHEMBL9196 | 0.69 | MAPT (0.36) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062804-A | 1, 3-substituted cyclobutyl derivatives and their use | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |