Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30048933 | 1.00 | CYP19A1 (0.50) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL1614645 | 0.81 | CYP3A4 (0.47) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL30589181 | 0.80 | CYP19A1 (0.50) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL24608491 | 0.80 | CYP19A1 (0.50) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL8606933 | 0.80 | CYP19A1 (0.50) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL74389 | 0.76 | KIF11 (0.61) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL29583584 | 0.76 | KIF11 (0.61) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL6090239 | 0.76 | CYP19A1 (0.49) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL25898561 | 0.74 | HDAC8 (0.42) | CYP19A1LMNAKIF11 | |
| SCHEMBL27996644 | 0.74 | CYP19A1 (0.57) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355531-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-05 | — | — | CN | disclosed |