Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24459267 | 0.83 | HTR7 (0.49) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL8490782 | 0.82 | TAAR1 (0.64) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL83159 | 0.81 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL17420764 | 0.80 | SMN1; SMN2 (0.50) | CA1CA2CA12CA14ALDH1A1 | |
| SCHEMBL28858018 | 0.80 | TAAR1 (0.75) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL3296809 | 0.80 | IDO1 (0.61) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL17266361 | 0.79 | IDO1 (0.41) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL29138530 | 0.78 | IDO1 (0.46) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL27583392 | 0.78 | IDO1 (0.59) | IDO1TAAR1CHRM2CHRM1CA1 | |
| SCHEMBL17939 | 0.78 | IDO1 (0.59) | IDO1TAAR1CHRM2CHRM1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603682-B | Dicyanomethylene-4H-pyran molecules with AIE effect, construction method and application | 华东理工大学 | 2024-07-26 | — | — | CN | disclosed |
| WO-2024005209-A1 | 1,4-CINEOLE DERIVATIVE AND INTERMEDIATE THEREOF, HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT, METHOD FOR USING HERBICIDE, AND METHOD FOR PREPARING AGROCHEMICAL COMPOSITION | 北興化学工業株式会社 | 2024-01-04 | — | — | WO | disclosed |
| US-11339146-B2 | Compositions and methods for viral sensitization | Ottawa Hospital Research Institute and University of Ottawa (CA) | 2022-05-24 | — | — | US | disclosed |
| CN-113603682-A | dicyanomethylene-4H-pyran molecule with AIE effect, construction method and application | 华东理工大学 | 2021-11-05 | — | — | CN | disclosed |
| EP-3845531-A1 | SUBSTITUTED PYRAZOLE FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Applied Pharmaceutical Science, Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2021023888-A1 | ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2021-02-11 | — | — | WO | disclosed |
| CN-110218182-B | IDO inhibitors | 南京亘泰医药技术有限公司 | 2021-01-26 | — | — | CN | disclosed |
| US-20200354351-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2020-11-12 | — | — | US | disclosed |
| US-10633470-B2 | Method of producing a conjugated diene polymer, a modified conjugated diene polymer, and a vinyl cis-polybutadiene composition | UBE INDUSTRIES, LTD. (JP) | 2020-04-28 | — | — | US | disclosed |
| US-10508163-B2 | Conjugated diene polymer and modified conjugated diene polymer produced using the same, rubber composition for tire, and rubber composition for rubber belt | UBE INDUSTRIES, LTD. (JP) | 2019-12-17 | — | — | US | disclosed |
| US-5935976-A | Antiviral ethers of aspartate protease substrate isosteres | NOVARTIS CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |
| US-5807891-A | RETROVIRUSES | NOVARTIS AG (CH) | 1998-09-15 | — | — | US | disclosed |
| US-5663200-A | CARBAMOYL PEPTIDE DERIVATIVES AS VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| CN-1132756-A | Antiviral ethers of aspartate protease substrate isosteres | CIBA GEIGY AG (CH) | 1996-10-09 | — | — | CN | disclosed |
| EP-0708085-A2 | Antiviral ethers of aspartate protease substrate isosteres | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | disclosed |
| CN-1112125-A | Acyloxyhexanoic acid derivatives | CIBA GEIGY AG (CH) | 1995-11-22 | — | — | CN | disclosed |
| EP-0291327-A2 | Aryl-substituted naphthalene, benzoxepine, benzazepine and benzocycloheptene derivatives | SCHERING CORPORATION (US) | 1988-11-17 | — | — | EP | disclosed |
| US-4631283-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0107398-A1 | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339146-B2 | Compositions and methods for viral sensitization | CD4, CD74, HLA-DRB1 | IDO1 1676/4885TAAR1 3601/4885CHRM2 4590/4885 |
| US-20200354351-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | CD4, CD74, HAVCR2 | IDO1 2212/4885TAAR1 3755/4885CHRM2 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.